Stable population coding for working memory coexists with heterogeneous neural dynamics in prefrontal cortex
نویسندگان
چکیده
منابع مشابه
Stable population coding for working memory coexists with heterogeneous neural dynamics in prefrontal cortex.
Working memory (WM) is a cognitive function for temporary maintenance and manipulation of information, which requires conversion of stimulus-driven signals into internal representations that are maintained across seconds-long mnemonic delays. Within primate prefrontal cortex (PFC), a critical node of the brain's WM network, neurons show stimulus-selective persistent activity during WM, but many...
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Working memory (WM) provides the stability necessary for high-level cognition. Influential theories typically assume that WM depends on the persistence of stable neural representations, yet increasing evidence suggests that neural states are highly dynamic. Here we apply multivariate pattern analysis to explore the population dynamics in primate lateral prefrontal cortex (PFC) during three vari...
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Rogier B. Mars1,2 and Meike J. Grol3,4 1Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology and 2Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, United Kingdom, 3Helmholtz Research Institute, Experimental Psychology, Utrecht University, 3584 CS Utrecht, The Netherlands, and 4F.C. Donders Centre for Cognitive Neuroimaging, Radbo...
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Some neurons (delay cells) in the prefrontal cortex elevate their activities throughout the time period during which the animal is required to remember past events and prepare future behavior, suggesting that working memory is mediated by continuous neural activity. It is unknown, however, how working memory is represented within a population of prefrontal cortical neurons. We recorded from neu...
متن کاملWorking Memory in the Prefrontal Cortex
The prefrontal cortex participates in a variety of higher cognitive functions. The concept of working memory is now widely used to understand prefrontal functions. Neurophysiological studies have revealed that stimulus-selective delay-period activity is a neural correlate of the mechanism for temporarily maintaining information in working memory processes. The central executive, which is the ma...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2016
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1619449114